The only person that is totally satisfied is The Lord Jesus. He is the only person who deserves to be totally satisfied. The only way the rest of us can have genuine satisfaction is to be like Him. The more like Him we become the more satisfied we will be.
Psalms 17:15: As for me, I will behold thy face in righteousness: I shall be satisfied, when I awake, with thy likeness.
In this flesh and in this world we can only become like Him by His presence in our hearts and then, as He controls them, in our actions. Without His presence within us we have zero spiritual resemblance to Him.
Ephesians 3:17: That Christ may dwell in your hearts by faith; that ye, being rooted and grounded in love,
2 Corinthians 4:6: For God, who commanded the light to shine out of darkness, hath shined in our hearts, to give the light of the knowledge of the glory of God in the face of Jesus Christ.
1 Thessalonians 3:13: To the end he may stablish your hearts unblameable in holiness before God, even our Father, at the coming of our Lord Jesus Christ with all his saints.
Life is always unsatisfying until it is given to the Lord. When someone has given his life to Christ and become a Christian it is inevitable that his flesh will take back portions of what he has given the Savior. The portions of his life that he takes back will be just as unsatisfying as his entire life was before.
The giant step from dissatisfaction to satisfaction is receiving Christ into one*s heart as Savior. After doing that we can make many daily steps out of the dissatisfaction of our flesh and into the satisfaction of His righteousness. Those steps happen as we trust and obey Him. Remarkably, our flesh is still so stupid that it steps away from what gives us satisfaction (righteousness) to what takes away satisfaction (sin).
Galatians 6:8: For he that soweth to his flesh shall of the flesh reap corruption; but he that soweth to the Spirit shall of the Spirit reap life everlasting.
Romans 8:7: Because the carnal mind is enmity against God: for it is not subject to the law of God, neither indeed can be.
One day we will be totally, eternally and irreversibly satisfied as He is.
1 Corinthians 15:52: In a moment, in the twinkling of an eye, at the last trump: for the trumpet shall sound, and the dead shall be raised incorruptible, and we shall be changed.
1 John 3:2: Beloved, now are we the sons of God, and it doth not yet appear what we shall be: but we know that, when he shall appear, we shall be like him; for we shall see him as he is.